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Predictive factors of epilepsy in arteriovenous malformation

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Abstract Objective Structural epilepsy related to cerebral arteriovenous malformation (AVM) suggests different epileptogenic mechanisms. The aim of our study was to determine factors associated with epilepsy into a retrospective cohort… Click to show full abstract

Abstract Objective Structural epilepsy related to cerebral arteriovenous malformation (AVM) suggests different epileptogenic mechanisms. The aim of our study was to determine factors associated with epilepsy into a retrospective cohort of AVM patients. Patients and methods Ruptured and unruptured AVM data retrieved from a prospective single center registry (2009–2016) were retrospectively assessed. Demographic, clinical and radiological features were identified in AVM patients with or without epilepsy according to the International League Against Epilepsy classification. Results Epilepsy concerned 22 out of 80 consecutive patients with AVM (27.5%). Univariate analysis comparing both groups revealed a significant association of different variables with the structural epilepsy: young age (P = 0.02), large nidus size (P = 0.02), venous dilation (P = 0.02), posterior cerebral artery (PCA) feeder (P  Conclusion PCA feeder for cerebral AVM was significantly associated with structural epilepsy. The hypothesis of a vascular steal phenomenon to the detriment of internal temporal lobe vascularization could be related to the development of epilepsy.

Keywords: structural epilepsy; epilepsy; arteriovenous malformation; avm; predictive factors

Journal Title: Neurochirurgie
Year Published: 2020

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