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The presence of protein aggregates within the central nervous system is intimately associated to debilitating neurodegenerative diseases. While the aggregation of proteins, that share no primary structure identity, is understandable… Click to show full abstract
The presence of protein aggregates within the central nervous system is intimately associated to debilitating neurodegenerative diseases. While the aggregation of proteins, that share no primary structure identity, is understandable in different diseases, that of a given protein yielding distinct pathologies is counterintuitive. This short review relates molecular and mechanistic processes to the observed pathological diversity.
Keywords:
pathological diversities;
amyloid polymorphs;
polymorphs pathological
Journal Title: Neurochemistry International
Year Published: 2022
Link to full text (if available)
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Journal Title: Neurochemistry International
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!