LAUSR

The behavioral effects of ethanol in brown planarians were studied in four experiments. In the first two experiments, acute administrations of ethanol increased travel time in a dose-dependent fashion in individual planarians moving away from a light source. Orderly results were obtained using both within-subject and between-group designs. In a third experiment, ethanol dose was arranged by time rather than concentration. Ethanol increased travel time overall, but variability between subjects was considerable. In a final experiment, ethanol administration reduced motility and altered movement patterns in planarians in an open-field test. These experiments demonstrated that negative phototaxis by planarians may exhibit sufficient stability to allow for experimental determinations of dose-response curves utilizing both within-subject and between-subject designs.