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Highlights • Dendritic complexity and presynaptic density are reduced in the 4R-tauopathies of PSP and CBD.• The reduction in ODI and UCB-J binding is coupled across the cortical mantle as… Click to show full abstract
Highlights • Dendritic complexity and presynaptic density are reduced in the 4R-tauopathies of PSP and CBD.• The reduction in ODI and UCB-J binding is coupled across the cortical mantle as well as subcortically.• The relationship between ODI and UCB-J binding is not attributed to atrophy.• ODI may be a useful biomarker of synaptic pathology in neurodegenerative diseases.
Keywords:
dendritic complexity;
presynaptic density;
vivo coupling;
complexity presynaptic
Journal Title: Neurobiology of Aging
Year Published: 2021
Link to full text (if available)
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Journal Title: Neurobiology of Aging
Year Published: 2021
Link to full text (if available)
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recommendations!