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In this issue of Neuron, Ishiguro et al. (2017) explore the toxicity of RAN translation in spinocerebellar ataxia 31. Using a Drosophila model, the authors demonstrate that TDP-43 and other RNA-binding… Click to show full abstract
In this issue of Neuron, Ishiguro et al. (2017) explore the toxicity of RAN translation in spinocerebellar ataxia 31. Using a Drosophila model, the authors demonstrate that TDP-43 and other RNA-binding proteins act as chaperones to regulate the formation of toxic RNA aggregates.
Keywords:
binding proteins;
rna;
rna binding;
ran translation;
sca31 flies
Journal Title: Neuron
Year Published: 2017
Link to full text (if available)
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Journal Title: Neuron
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!