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Revealing a Role for NMDA Receptors in Regulating STN Inputs following the Loss of Dopamine

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In this issue of Neuron, Chu et al. (2017) show that dopamine depletion using a 6-OHDA model causes a decrease in hyperdirect inputs from the motor cortex directly to the STN… Click to show full abstract

In this issue of Neuron, Chu et al. (2017) show that dopamine depletion using a 6-OHDA model causes a decrease in hyperdirect inputs from the motor cortex directly to the STN and that rescuing this loss alleviates Parkinsonian symptoms.

Keywords: receptors regulating; role nmda; revealing role; nmda receptors; regulating stn; loss

Journal Title: Neuron
Year Published: 2017

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