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Phase-Amplitude Coupling: A General Mechanism for Memory Processing and Synaptic Plasticity?

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In this issue of Neuron, Helfrich et al. (2017) demonstrate that phase-amplitude coupling (PAC) between slow oscillations and spindles is crucial for memory consolidation, and shifts in its phase relationship may… Click to show full abstract

In this issue of Neuron, Helfrich et al. (2017) demonstrate that phase-amplitude coupling (PAC) between slow oscillations and spindles is crucial for memory consolidation, and shifts in its phase relationship may explain age-related deficits in memory performance. These results also suggest a more general function of PAC in synaptic plasticity.

Keywords: synaptic plasticity; phase amplitude; memory; amplitude coupling

Journal Title: Neuron
Year Published: 2018

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