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In this issue of Neuron, Liao and colleagues (2018) uncover a surprising way that the guidance molecule MIG14/Wntless operates in dendrite self-avoidance in sensorimotor neurons. Not only does MIG14/Wntless not… Click to show full abstract
In this issue of Neuron, Liao and colleagues (2018) uncover a surprising way that the guidance molecule MIG14/Wntless operates in dendrite self-avoidance in sensorimotor neurons. Not only does MIG14/Wntless not require the soluble cue Wntless, but it can mediate direct cell-cell contact at the plasma membrane. During dendrite tip contact, MIG14/Wntless drives local bursts of WASP-dependent actin filament assembly that facilitate sister dendrite repulsion.
Keywords:
self avoidance;
sibling conflict;
dendrite self;
avoiding sibling;
mig14 wntless
Journal Title: Neuron
Year Published: 2018
Link to full text (if available)
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Journal Title: Neuron
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!