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Small RNAs, but Sizable Itch: TRPA1 Activation by an Extracellular MicroRNA

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Chronic itch is a major symptom of cutaneous T cell lymphoma (CTCL). In this issue of Neuron, Han and colleagues (2018) provide evidence that one of the itch mediators in CTCL… Click to show full abstract

Chronic itch is a major symptom of cutaneous T cell lymphoma (CTCL). In this issue of Neuron, Han and colleagues (2018) provide evidence that one of the itch mediators in CTCL is an extracellular miRNA that directly activates TRPA1 on sensory neurons.

Keywords: itch; itch trpa1; trpa1 activation; small rnas; rnas sizable; sizable itch

Journal Title: Neuron
Year Published: 2018

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