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Not Fade Away: Mechanisms of Neuronal ATP Homeostasis

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In this issue of Neuron, Ashrafi et al. (2020) identify a feedforward signaling mechanism that couples neuronal activity to the homeostatic maintenance of axonal and synaptic ATP production. This mechanism is… Click to show full abstract

In this issue of Neuron, Ashrafi et al. (2020) identify a feedforward signaling mechanism that couples neuronal activity to the homeostatic maintenance of axonal and synaptic ATP production. This mechanism is achieved via changes in cytoplasmic calcium and activation of brain-specific, mitochondrial MICU3.

Keywords: atp; fade away; away mechanisms; neuronal atp; atp homeostasis; mechanisms neuronal

Journal Title: Neuron
Year Published: 2020

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