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A M/EEG-fMRI Fusion Primer: Resolving Human Brain Responses in Space and Time

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Any cognitive function is mediated by a network of many cortical sites whose activity is orchestrated through complex temporal dynamics. To understand cognition, we need to identify brain responses simultaneously… Click to show full abstract

Any cognitive function is mediated by a network of many cortical sites whose activity is orchestrated through complex temporal dynamics. To understand cognition, we need to identify brain responses simultaneously in space and time. Here we present a technique that does this by linking multivariate response patterns of the human brain recorded with functional magnetic resonance imaging (fMRI) and with magneto- or electroencephalography (M/EEG) based on representational similarity. We present the rationale and current applications of this non-invasive analysis technique, termed M/EEG-fMRI fusion, and discuss its pros and cons. We highlight its wide applicability in cognitive neuroscience and how its openness to further development and extension gives it strong potential for a deeper understanding of cognition in the future.

Keywords: brain responses; space time; human brain; fmri fusion; brain; eeg fmri

Journal Title: Neuron
Year Published: 2020

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