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In this issue of Neuron, Boivin et al. (2021) show that a polyglycine-expanded protein, uN2CpolyG, is translated from an expansion of GGC repeats in the 5' UTR of the NOTCH2NLC (Notch… Click to show full abstract
In this issue of Neuron, Boivin et al. (2021) show that a polyglycine-expanded protein, uN2CpolyG, is translated from an expansion of GGC repeats in the 5' UTR of the NOTCH2NLC (Notch homolog 2 N-terminal-like C) gene, defining a new pathological mechanism for neuronal intranuclear inclusion diseases (NIID).
Keywords:
protein;
inclusion disease;
intranuclear inclusion;
polyglycine;
neuronal intranuclear
Journal Title: Neuron
Year Published: 2021
Link to full text (if available)
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Journal Title: Neuron
Year Published: 2021
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!