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Back-to-BACs in Huntington’s disease modeling

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In this issue of Neuron, Gu et al. (2022) describe a new BAC mouse model that faithfully recapitulates various aspects of Huntington's disease pathobiology and reveals important insights into the relative… Click to show full abstract

In this issue of Neuron, Gu et al. (2022) describe a new BAC mouse model that faithfully recapitulates various aspects of Huntington's disease pathobiology and reveals important insights into the relative toxicities of mHTT-derived products.

Keywords: back bacs; disease modeling; huntington disease; bacs huntington; disease

Journal Title: Neuron
Year Published: 2022

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