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Mutations in epigenetic factors are associated with autism spectrum disorder (ASD). In this issue of Neuron, Yan et al. (2022) show that the antagonism of ASH1L and PRC2 switches the equilibrium… Click to show full abstract
Mutations in epigenetic factors are associated with autism spectrum disorder (ASD). In this issue of Neuron, Yan et al. (2022) show that the antagonism of ASH1L and PRC2 switches the equilibrium of histone methylation at the ephrin receptor A7 locus, causing decreased EphA7 expression, deficits in synaptic pruning, and ASD-like behaviors.
Keywords:
social actions;
epigenetic switch;
controls social;
switch controls
Journal Title: Neuron
Year Published: 2022
Link to full text (if available)
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Journal Title: Neuron
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!