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Highlights • Attention and stimulus selection deficits in Gdi1-null Intellectual Disability model.• Behavioral deficits correlated with fronto-striatal system dysfunction.• A major role for glutamatergic activity in fronto-striatal circuitry dysfunction.• Correlation… Click to show full abstract
Highlights • Attention and stimulus selection deficits in Gdi1-null Intellectual Disability model.• Behavioral deficits correlated with fronto-striatal system dysfunction.• A major role for glutamatergic activity in fronto-striatal circuitry dysfunction.• Correlation between reported patient’s cognitive deficits and present findings.
Keywords:
altered fronto;
intellectual disability;
gdi1 null;
model;
fronto striatal
Journal Title: Neuroscience
Year Published: 2017
Link to full text (if available)
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Journal Title: Neuroscience
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!