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Highlights • We have established a novel human astrocyte-neuron co-culture system.• Astrocytes provided contact-mediated support for neurite outgrowth.• IGF1R-impaired astrocytes are less able to protect neurons under stress conditions.• Microarray… Click to show full abstract
Highlights • We have established a novel human astrocyte-neuron co-culture system.• Astrocytes provided contact-mediated support for neurite outgrowth.• IGF1R-impaired astrocytes are less able to protect neurons under stress conditions.• Microarray analysis of these astrocytes identified changes in energy metabolism.
Keywords:
loss igf1r;
human astrocytes;
astrocytes alters;
igf1r;
igf1r human;
support
Journal Title: Neuroscience
Year Published: 2018
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Journal Title: Neuroscience
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!