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Azole-resistant Candida blankii as a newly recognized cause of bloodstream infection

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Candida blankii is a newly recognized human pathogen. Here we describe a case of bloodstream infection in a preterm neonate. The yeast was repeatedly isolated from blood, and its identity… Click to show full abstract

Candida blankii is a newly recognized human pathogen. Here we describe a case of bloodstream infection in a preterm neonate. The yeast was repeatedly isolated from blood, and its identity was confirmed by PCR sequencing of rDNA. Additionally, C. blankii DNA was detected directly in a blood sample. The isolates initially developed pink colonies on CHROMagar Candida which later turned into dark metallic blue similar to Candida tropicalis. Inaccurate identification by the VITEK 2 yeast identification system as Stephanoascus ciferrii and intrinsic resistance to fluconazole (MIC 12–16 μg/mL) underscore the need for its accurate identification for appropriate therapeutic management.

Keywords: bloodstream infection; candida; candida blankii; newly recognized; blankii newly

Journal Title: New Microbes and New Infections
Year Published: 2018

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