LAUSR

Background Blood group antigens are one of the most important antigens in humans that have an impact on susceptibility to disease and may be used as a prognosis factor in different diseases such as covid-19. Objectives Study aimed to investigate the relationship between ABO blood groups and Rhesus antigen and susceptibility to COVID-19. Methods The clinical data of 398 subjects were used in the investigation collected from 148 cases vs. 250 controls. This information was obtained from Shahid Sadoughi Hospital of Yazd (IRAN) University. blood groups and outcomes was assessed using statistical tests for four populations: COV + vs. COV− and COV +/deceased vs. COV +/live. Results Out of a total of 148 COVID19 patients, 80 (54/1%) were male, 68 (45/9%) were female. Among these patients 33 (22/6%) had type A+, 44 (30/1%) had type B+, 13 (8/9%) had type AB+ and 36 (24/7%) had type O+. On the other hand, out of a 148 patients, 126 (86/3%) had positive blood types and 20 (13/7%) had negative blood types. As a result, no significant difference was found in the relationship between ABO blood groups and RH type and susceptibility to COVID-19 (p-value= 0.392 and p-value=0.847, respectively). Other data showed a significant difference between patients group with other parameters such as age (p-value<0.001) and gender (p-value<0.001). Conclusion Although in this study there was no association between blood type and RH type with COVID-19, findings about association between age and gender can confirm the results of previous studies.