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Brain perfusion SPECT with 99mTc-HMPAO in the diagnosis and follow-up of patients with anti-NMDA receptor encephalitis.

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Anti-N-methyl-d-aspartate (NMDA) receptor encephalitis was first described in 2007. The most frequent forms result from extracellular antibody-mediated autoimmunity. Prognosis improves with early, aggressive immunotherapy; aetiological diagnosis is therefore essential. Diagnosis… Click to show full abstract

Anti-N-methyl-d-aspartate (NMDA) receptor encephalitis was first described in 2007. The most frequent forms result from extracellular antibody-mediated autoimmunity. Prognosis improves with early, aggressive immunotherapy; aetiological diagnosis is therefore essential. Diagnosis is based on the detection of anti-NMDA receptor antibodies in the serum and cerebrospinal fluid (CSF). MRI usually shows normal findings or mild alterations. Given the lack of specificity and the frequently subacute onset of symptoms, brain

Keywords: receptor encephalitis; diagnosis; nmda receptor; anti nmda; receptor

Journal Title: Neurologia
Year Published: 2018

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