LAUSR

Originally received: August 15, 2016. Final revision: September 21, 2016. Accepted: September 28, 2016. Available online: November 15, 2016. Manuscript no. 2016-87. 1 Departments of Ophthalmology and Public Health Sciences, Penn State Eye Center, Penn State College of Medicine, Hershey, Pennsylvania. 2 The Emmes Corporation, Rockville, Maryland. 3 Doheny Eye Institute, University of California, Los Angeles, California. 4 University of Wisconsin Fundus Photograph Reading Center, Madison, Wisconsin. 5 Retinal Consultants of Arizona, Phoenix, Arizona. 6 USC Roski Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, California. Presented in part at the Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO), May 1e5, 2016, Seattle, Washington. Financial Disclosure(s): Supported by National Eye Institute (National Institutes of Health, Department of Health and Human Services) grants U10EY023529, U10EY023533, and U10EY023521. Support also provided in part by Regeneron, Inc., and Allergan, Inc., through donation of investigational drug. Author Contributions: Conception and design: Scott, VanVeldhuisen, Ip, Blodi, Oden, Figueroa Analysis and interpretation: Scott, VanVeldhuisen, Ip, Blodi, Oden, Figueroa, Dugel