LAUSR

Presented at: American Academy of Ophthalmology 2015; Association for Research in Vision and Ophthalmology 2016. Financial Disclosure(s): Supported by Alimera Sciences Inc., Alpharetta, GA. The funding organization participated in the conduct of the study, and the data collection, data management, and data analysis of this research, and provided financial support for medical writing services by Helios Medical Communications, Alderley Edge, Cheshire, UK. C.W.: Grants e Acucela, Allegro Ophthalmics, Ampio Pharmaceuticals, Apellis Pharmaceuticals, DRCR network/NEI, Iconic Therapeutics, Ophthotech, Pfizer, Santen, pSivida, Tyrogenex, and Xoma; Grants and personal fees e Alcon Laboratories, Inc., Allergan, Clearside Biomedical, Inc., Genentech/Roche, Regeneron Pharmaceuticals, and ThromboGenics, Inc.; Personal fees e Alimera Sciences, Bayer, and DORC International; Personal fees and other e ONL Therapeutics, outside the submitted work. U.C.: Personal fees e Alimera Sciences, during the conduct of the study; Personal fees e Allergan, outside the submitted work. P.C.: Grants and personal feeseAlimera and Allergan during the conduct of the study; Grants e Abbvie, Genzyme, GlaxoSmithKline, and Regeneron; Personal fees e Allegro, Applied Genetic Technologies, Intrexon, and Merck; Grants and personal feeseAerpio, AsclipiX, Genentech/Roche, and Regenexbio; Personal fees and othereGraybug, outside the submitted work. C.B.: Financial support e Alcon, Allergan, Alimera Sciences, Bayer, and Novartis in the form of research funding, grants, research materials, or inkind services. K.G.: Employee and stockholder e Alimera Sciences. J.C.V.: Consultant e Alimera Sciences, Allergan, Bayer, Gene Signal, Novartis, Pfizer, Precision Ocular Ltd., Roche, Sanofi-Aventis, Vifor Pharma, and Carl Zeiss Meditec. Author Contributions: Conception and design: Wykoff, Chakravarthy, Campochiaro, Bailey, Green, Cunha-Vaz Analysis and interpretation: Wykoff, Chakravarthy, Campochiaro, Bailey, Green, Cunha-Vaz Data collection: Wykoff, Chakravarthy, Campochiaro, Bailey, Green, Cunha-Vaz Obtained funding: Not applicable Overall responsibility: Wykoff, Chakravarthy, Campochiaro, Bailey, Green, Cunha-Vaz Abbreviations and Acronyms: DME 1⁄4 diabetic macular edema; DR 1⁄4 diabetic retinopathy; DRCR.net 1⁄4 Diabetic Retinopathy Clinical Research Network; DRSS 1⁄4 diabetic retinopathy severity scale; ETDRS 1⁄4 Early Treatment Diabetic Retinopathy Study; FAc 1⁄4 fluocinolone acetonide; FAME 1⁄4 Fluocinolone Acetonide in Diabetic Macular Edema; IOP 1⁄4 intraocular pressure; NPDR 1⁄4 nonproliferative diabetic retinopathy; PDR 1⁄4 proliferative diabetic retinopathy; PPV 1⁄4 pars plana vitrectomy; PRP 1⁄4 panretinal photocoagulation; VEGF 1⁄4 vascular endothelial growth factor-A. Correspondence: Charles C. Wykoff, MD, PhD, Retina Consultants of Houston, Blanton Eye Institute, Houston Methodist Hospital, Houston, TX 77030. E-mail: [email protected].