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Rapid microwave synthesis of N-doped carbon nanodots with high fluorescence brightness for cell imaging and sensitive detection of iron (III)

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Abstract We rapidly prepared N-doped photoluminescent carbon nanodots (CNDs) with the one-step microwave irradiation method using diammonium hydrogen citrate as the carbon source. The as-prepared CNDs possessed quasispherical morphology and… Click to show full abstract

Abstract We rapidly prepared N-doped photoluminescent carbon nanodots (CNDs) with the one-step microwave irradiation method using diammonium hydrogen citrate as the carbon source. The as-prepared CNDs possessed quasispherical morphology and a high quantum yield of about 26.8%, which was higher than the CNDs obtained by most other microwave-assisted methods. Moreover, the luminescent CNDs could be efficiently uptaken by BGC-823 cells and CT26.WT cells, and exhibited low cytotoxicity and favorable biocompatibility, making them suitable candidates for cell imaging. In addition, the CNDs could be utilized for Fe3+ ions sensitive detection with a detection limit of 180 nM.

Keywords: rapid microwave; detection; cell imaging; carbon; carbon nanodots; sensitive detection

Journal Title: Optical Materials
Year Published: 2017

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