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Full thickness chondral defects can be debilitating for athletes. Due to the low potential for intrinsic healing of articular cartilage, surgical intervention is often considered when patients continue to experience… Click to show full abstract
Full thickness chondral defects can be debilitating for athletes. Due to the low potential for intrinsic healing of articular cartilage, surgical intervention is often considered when patients continue to experience functionally limiting symptoms despite an adequate trial of nonoperative management. Matrix-induced autologous chondrocyte implantation (MACI) is a 2-stage procedure used to treat chondral lesions with minimal subchondral bone involvement. MACI has significant advantages over previous generations of autologous chondrocyte implantation (ACI), including a simplified surgical technique and accelerated postoperative rehabilitation protocol. MACI has been shown to result in good clinical outcomes, with several studies showing high success rates. Additionally, MACI has a low rate of complications specific to the procedure.
Journal Title: Operative Techniques in Sports Medicine
Year Published: 2020
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