LAUSR

The SARS-CoV-2 has left a huge impact on death balance associated with COVID-19 around the world. There is a high proportion of these patients with diabetes, who have been documented to have more significant mortality and serious complication. Recently, abnormal fasting blood glucose (FBG) levels have been associated with increased death risk in Covid-19 patients. Besides, high HbA1c levels in those patients during admission, with diabetes or without as well. These results are associated with proinflammatory activity, prothrombotic states, and low levels of oxygen saturation (SaO 2 ). Additionally, it has been observed a relationship between increased risk of mortality and higher levels of HbA1c. Thus, HbA1c has been proposed as a risk stratification marker. This work objective was to evaluate HbA1c as a complication and risk predictive mortality marker in patients with or without diabetes with Covid-19 at admission. A retrospective analysis of clinical and laboratory data obtained from Covid-19 patients at admission to intensive care services in the IMSS Hospital in Celaya, from August 13 to September 02, 2020. Statistical analysis was done by using twosamples Student t -test for continuous data and Aspin-Welch test when unequal variances. The χ 2 test for trend analysis resolved qualitative categorical data. Higher values of FBG and HbA1c in Mexican Covid19 patients were observed, independently if they had been diagnosed with diabetes. However, this finding is not associated with higher mortality, and it is not necessarily dependent on respiratory complications but with prothrombotic activity.