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5-Aminolevulinic acid induced photodynamic therapy (ALA-PDT) for erosive adenomatosis of the nipple: a case report.

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Erosive adenomatosis of the nipple (EAN) is a very uncommon, benign neoplasm that involves the nipple. Generally, complete surgical excision is the main treatment, and we can take alternative therapeutic… Click to show full abstract

Erosive adenomatosis of the nipple (EAN) is a very uncommon, benign neoplasm that involves the nipple. Generally, complete surgical excision is the main treatment, and we can take alternative therapeutic methods such as Mohs micrographic surgery and cryotherapy into consideration. Here, we report a case of a 40-year-old woman with a 2-year history of asymptomatic erosion, papillomatous hyperplasia and intermittent serosanguineous discharge from right nipple. Histopathological examination confirmed diagnosis of EAN. She was treated with 5-aminolevulinic acid induced photodynamic therapy (ALA-PDT) for 2 times with 2 weeks intervals. No recurrence occurred within 6 months. Therefore, we consider that ALA-PDT might be an alternative treatment for erosive adenomatosis of nipple, especially in the early stage that represent with erosion and mild serous exudation.

Keywords: ala pdt; adenomatosis nipple; photodynamic therapy; erosive adenomatosis

Journal Title: Photodiagnosis and photodynamic therapy
Year Published: 2021

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