LAUSR

AIM To compare the choroidal structural components and choroidal vascularity index (CVI) between patients with obstructive sleep apnea syndrome (OSAS) and healthy controls. METHODS The choroidal images of the eyes of patients with OSAS and healthy controls, which were obtained by using enhanced depth imaging optical coherence tomography (EDI-OCT), were binarized into luminal area (LA) and stromal area (SA) using the ImageJ software. CVI was calculated as the ratio of LA to the total choroid area (TCA). The CVI, LA, SA, and TCA measurements were compared between the groups. RESULTS Seventy-one eyes of 57 patients, 33 eyes of 27 patients with OSAS and 38 eyes of 30 healthy individuals, were included. The mean age of all patients was 46.77±9.75 (range, 30-67) years. There was no statistically significant difference for age, sex, axial length (AL) or the side of the eyes between the groups (p>0.05). The mean body mass index (BMI) of the patients was significantly higher in the OSAS group (p<0.05). The mean CVI value was 68.33±1.81% in the OSAS group and 69.21±1.27% in the control group (p<0.05). There was no statistically significant difference for the mean values of LA, SA, and TCA between the groups (p>0.05). No significant correlation was found between the polysomnography test results and the choroidal measurements (p>0.05). CONCLUSION In our study, CVI was found to be lower in patients with OSAS than in the healthy controls. Further studies with larger sample sizes are required to evaluate the role of CVI in OSAS.