LAUSR

Clinical Features That Raise Suspicion for MODY. Type 1 (T1) and type 2 (T2) diabetes mellitus (DM) are the most commonly recognized disease states characterized by hyperglycemia. However, diabetes compromises many disorders with hyperglycemia as a common feature. Other forms of diabetes include gestational diabetes, neonatal diabetes, cystic fibrosis-related diabetes, latent autoimmune diabetes in adults, and maturity-onset diabetes of the young (MODY). MODY affects pediatric patients and accounts for 2–5% of all diabetes cases (Timsit, Bellanné-Chantelot, Dubois-Laforgue, & Velho, 2005). Accurate diagnosis is imperative as it impacts treatment, complication surveillance, family screening and genetic counseling. Limited awareness of MODY, its characteristics, and diagnostic methods is an obstacle to proper diagnosis and treatment. This article provides an overview of MODY and a framework for identifying potential cases.