Highlights • Quantified variation in delivered dose due to sub-components of output uncertainty.• Largest uncertainty in delivered dose identified as pre-treatment output drift.• Potential clinical consequences of such uncertainties quantified.•… Click to show full abstract
Highlights • Quantified variation in delivered dose due to sub-components of output uncertainty.• Largest uncertainty in delivered dose identified as pre-treatment output drift.• Potential clinical consequences of such uncertainties quantified.• Uncertainty within the dosimetry chain may be significant for clinical trials.
               
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