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Positron emission tomography guided dose painting by numbers of lung cancer: Alanine dosimetry in an anthropomorphic phantom

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Highlights • DPBN was delivered to a phantom based on the anatomy of a lung cancer patient examined by FDG PET/CT prior to radiotherapy.• Alanine dosimetry showed that DPBN can… Click to show full abstract

Highlights • DPBN was delivered to a phantom based on the anatomy of a lung cancer patient examined by FDG PET/CT prior to radiotherapy.• Alanine dosimetry showed that DPBN can be delivered with high accuracy to the tumour in the anthropomorphic phantom.• For regions outside the tumour, high correspondence between planned and delivered doses were also found.• Positioning errors can lead to large deviations and potentially sub-optimal tumor doses.

Keywords: alanine dosimetry; anthropomorphic phantom; lung cancer; phantom

Journal Title: Physics and Imaging in Radiation Oncology
Year Published: 2022

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