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Angiotensin receptor blockers for the treatment of COVID-19 and its comorbidities

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My recent report (Saavedra, 2020a) warned about the danger of removing ARBs from patients suffering from COVID-19 comorbidities, calling for definitive data analysis to determine whether ARB administration benefited COVID-19… Click to show full abstract

My recent report (Saavedra, 2020a) warned about the danger of removing ARBs from patients suffering from COVID-19 comorbidities, calling for definitive data analysis to determine whether ARB administration benefited COVID-19 patients. Huang and colleagues disagreed with my proposal. Based on preliminary information, they believed ARBs could not benefit COVID-19 patients and that increase in RAS activity was a simple concomitant symptom of COVID-19 with no bearing on the disease outcome. Here we report a summary of the evidence on the protective effects of ARBs on COVID-19 comorbidities and lung function, and the multiple ongoing clinical studies to determine the effect of ARBs on COVID-19 patients.

Keywords: covid patients; receptor blockers; covid comorbidities; blockers treatment; covid; angiotensin receptor

Journal Title: Pharmacological Research
Year Published: 2020

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