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Abstract Two new compounds, named leptospyranonaphthazarin A ( 1 ) and leptosnaphthoic acid A ( 2 ), together with four known compounds ( 3–6 ) were isolated from an endophytic… Click to show full abstract
Abstract Two new compounds, named leptospyranonaphthazarin A ( 1 ) and leptosnaphthoic acid A ( 2 ), together with four known compounds ( 3–6 ) were isolated from an endophytic fungus Leptosphaerulina sp. SKS032. Their structures were assigned using spectroscopic methods, computational methods, and single-crystal X-ray diffraction analysis. In the antibiotic assay, compounds 1 , 2 , and 6 exhibited antibacterial activities against Staphylococcus aureus with minimal inhibitory concentration (MIC) values of 25.0, 50.0, and 50.0 μg/mL, respectively.
Journal Title: Phytochemistry Letters
Year Published: 2017
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