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Abstract Three new cassane-type diterpenoids named caesalppans G-I (1–3) together with three known ones (4–6), were isolated from the methanol extract of Caesalpinia sappan seeds. Their structures were determined based… Click to show full abstract
Abstract Three new cassane-type diterpenoids named caesalppans G-I (1–3) together with three known ones (4–6), were isolated from the methanol extract of Caesalpinia sappan seeds. Their structures were determined based on spectroscopic data. Among the isolated compounds, compound 2 displayed a moderate antimalarial activity with an IC50 value of 2.4 μM, and compound 4 showed mild anti-inflammatory activity with an IC50 value of 28.65 μM.
Keywords:
cassane diterpenoids;
diterpenoids seeds;
bioactive cassane;
cassane;
caesalpinia sappan;
seeds caesalpinia
Journal Title: Phytochemistry Letters
Year Published: 2017
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Journal Title: Phytochemistry Letters
Year Published: 2017
Link to full text (if available)
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recommendations!