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Abstract Four new lanostane triterpenes together with twenty-two known lanostane triterpenes were isolated from the epidermis of Poria cocos . The chemical structures of all compounds were determined mainly by… Click to show full abstract
Abstract Four new lanostane triterpenes together with twenty-two known lanostane triterpenes were isolated from the epidermis of Poria cocos . The chemical structures of all compounds were determined mainly by 1D and 2D-NMR spectrometry. Three of the new compounds ( 5 , 10 and 24 ) were evaluated for cytotoxic activities against human gastric carcinoma MGC-803, human hepatocellular carcinoma HepG2, and African green monkey kidney (VERO) cell lines in vitro . The results showed that only compound 10 showed weak cytotoxic activities on MGC-803 and HepG2 cell lines with IC 50 values at 42.90, 44.07 μM, respectively.
Journal Title: Phytochemistry Letters
Year Published: 2017
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