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Four new phenylpropanoid glycosides from Clausena dunniana var. robustaand their antiinflammatory activities

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Abstract Four new phenylpropanoid glycosides, clausenaglycosides A–D (1–4), along with fourteen known compounds (5–18) were isolated from the leaves and twigs of Clausena dunniana var. robusta. The structures of the… Click to show full abstract

Abstract Four new phenylpropanoid glycosides, clausenaglycosides A–D (1–4), along with fourteen known compounds (5–18) were isolated from the leaves and twigs of Clausena dunniana var. robusta. The structures of the isolated compounds were determined by a combination of 1D and 2D NMR, MS, and CD spectroscopic data. The NF-κB inhibitory activity was evaluated in HeLa cells. Compound 17 displayed a moderate inhibition against NF-κB activation.

Keywords: four new; phenylpropanoid glycosides; clausena dunniana; dunniana var; new phenylpropanoid

Journal Title: Phytochemistry Letters
Year Published: 2017

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