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Benzofurans, benzoic acid derivatives, diterpenes and pyrrolizidine alkaloids from Peruvian Senecio

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Abstract Sixteen compounds incluiding four benzofurans (1–4), three benzoic acid derivatives (6–8), one eremophilane (9), four diterpenes (10–13) and four pyrrolizidine alkaloids (14–17) were isolated from Senecio subcandidus, S. klugii… Click to show full abstract

Abstract Sixteen compounds incluiding four benzofurans (1–4), three benzoic acid derivatives (6–8), one eremophilane (9), four diterpenes (10–13) and four pyrrolizidine alkaloids (14–17) were isolated from Senecio subcandidus, S. klugii and S. ayapatensis from Peru. Compounds 1–4 and 6–9 have not been previously reported as natural products. Their molecular structures were determined by NMR spectroscopic analysis, comparison with published NMR data and chemical transformations. The X-ray analysis of acetylated derivative 5 and compound 7 were also performed. Their insecticidal and antifungal activities were tested.

Keywords: pyrrolizidine alkaloids; diterpenes pyrrolizidine; benzoic acid; acid derivatives; derivatives diterpenes; benzofurans benzoic

Journal Title: Phytochemistry Letters
Year Published: 2018

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