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Abstract One new hemiterpene glycoside, securiterpenoside G (1), one new furolactone-type lignan glycoside, (7R,8R,8′S)-glaberide I 4-O-β-D-glucopyranosyl-(1‴→4″)-O-β-D-glucopyranoside (2), along with two known lignan glycosides, (7R,8R,8′S)-glaberide I 4-O-β-D-glucopyranoside (3) and (7S,7′S,8R,8′R)-4,4′-dihydroxy-3,5,3′,5′tetramethoxy-7,9′:7′,9-diepoxylignane-4-O-β-D-glucopyranosyl-(1→4)-O-β-D-glucopyranoside (4)… Click to show full abstract
Abstract One new hemiterpene glycoside, securiterpenoside G (1), one new furolactone-type lignan glycoside, (7R,8R,8′S)-glaberide I 4-O-β-D-glucopyranosyl-(1‴→4″)-O-β-D-glucopyranoside (2), along with two known lignan glycosides, (7R,8R,8′S)-glaberide I 4-O-β-D-glucopyranoside (3) and (7S,7′S,8R,8′R)-4,4′-dihydroxy-3,5,3′,5′tetramethoxy-7,9′:7′,9-diepoxylignane-4-O-β-D-glucopyranosyl-(1→4)-O-β-D-glucopyranoside (4) were isolated from the roots of Securidaca inappendiculata Hassk. The elucidation of their structures was based on the information of 1D, 2D NMR, HRESIMS, ECD, and the comparisons to published data. In addition, compounds 1 and 2 were evaluated for the anti-inflammatory activity against NO induced models.
Journal Title: Phytochemistry Letters
Year Published: 2020
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