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Abstract Bark exudate of the tree Commiphora swynnertonii Burtt. (Burseraceae) is used by ethnic groups in Northern Tanzania and Southern Kenya, to treat various diseases in humans and to kill… Click to show full abstract
Abstract Bark exudate of the tree Commiphora swynnertonii Burtt. (Burseraceae) is used by ethnic groups in Northern Tanzania and Southern Kenya, to treat various diseases in humans and to kill ectoparasites infesting livestock. The acaricidal activity has been demonstrated in vitro and in vivo. The aim of this study was to isolate the main constituents of the exudate. The exudate was fractionated by Flash Chromatography, purified by HPLC-SPE and subjected to NMR analysis for structural elucidation. Five furanosesquiterpenoids were isolated and identified as 6-oxodendrolasin, (E)-6-oxoisodendrolasin, (Z)-6-oxoisodendrolasin, crassifolone and 7,8-dihydroisodendrolasin, the latter one being reported here for the first time.
Journal Title: Phytochemistry Letters
Year Published: 2020
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