LAUSR

Abstract In this study, we focused on the antioxidant activities in NRK52e cells, a rat renal proximal tubular cell line, of five new phenylpropanoid glycosides, paulowninosides B–F (Compounds 1–5), which were isolated from the n-BuOH soluble part of the 50 % acetone-H2O extract of the flowers of Paulownia fortunei. The structures of the compounds were determined by extensive spectroscopic analyses (UV and IR spectroscopy, HR-ESI-MS, 1D-, 2D-NMR). The levels of antioxidant activities of the compounds were determined by real-time cell analysis (RTCA) of NRK52e cells that underwent H2O2-induced oxidative injury. Compounds 1, 3 and 5 exhibited excellent antioxidant activities compared with control group.