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Clarification and 3-D visualization of immunolabeled human placenta villi.

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We report here the successful 3D visualization of human placenta villous structures on the order of ∼1 mm3 by a combination of immunolabeling, rapid tissue clarification and laser scanning confocal microscopy.… Click to show full abstract

We report here the successful 3D visualization of human placenta villous structures on the order of ∼1 mm3 by a combination of immunolabeling, rapid tissue clarification and laser scanning confocal microscopy. The resultant image sets exhibit a complex arrangement of villi and their contained vasculature that mirrors their arrangement in situ.

Keywords: clarification visualization; human placenta; villi; placenta

Journal Title: Placenta
Year Published: 2017

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