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Abstract Mixed ligand complexes [Cu(phen)(Lap)2] (1) and [Co(dppeO)(Lap)2] (2) were synthesized from the reaction of lapachol (Lap) with [Cu(phen)Cl2] or [Co(dppe)Cl2] in the presence of Et3N. Complexes (1) and (2)… Click to show full abstract
Abstract Mixed ligand complexes [Cu(phen)(Lap)2] (1) and [Co(dppeO)(Lap)2] (2) were synthesized from the reaction of lapachol (Lap) with [Cu(phen)Cl2] or [Co(dppe)Cl2] in the presence of Et3N. Complexes (1) and (2) were fully characterized by X-ray crystallography, elemental analyses, and infrared spectroscopy. Antiproliferative activities of complexes (1) and (2) against several tumor cell lines were also determined alongside those of [Cu(Lap)2(EtOH)2] (3) and [Co(Lap)2(EtOH)2] (4).
Keywords:
synthesis characterization;
ligand complexes;
lapachol;
mixed ligand;
characterization antiproliferative
Journal Title: Polyhedron
Year Published: 2019
Link to full text (if available)
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Journal Title: Polyhedron
Year Published: 2019
Link to full text (if available)
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recommendations!