LAUSR

Abstract How to quantitatively design the loading time and amount of seed is a critical problem in the seeded crystallization process. In this study, correlations for different moment of crystal size distribution (CSD) function were established by subsection induction. By using the established different moment of CSD function, a new algorithm for kinetic model that can estimate the nucleation and growth kinetic parameters was proposed. Compared with kinetic model based on the conventional moments method, the new algorithm has a great significance since the overall heat transfer coefficient U is no longer necessary in the entire calculation. Using experimental data from literature, kinetic parameters of crystallization of KNO3 aqueous solution and xylene solution were estimated by the new algorithm, which are in good accordance with those fitting with moments method. This agreement shows the feasibility of the new algorithm. Finally, since it is difficult to measure transmittance data r of some systems, a criterion K that can identify nucleation and crystal growth stages without transmittance data was established. By means of the K curve of para-xylene (PX) and vitamin C, which is based on kinetic simulation results from the new algorithm and different moment of CSD function established by subsection induction, the single step seed load and two steps seed load were designed, respectively.