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Kidney transplant cortical necrosis observed during pelvic radiation therapy.

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A 61 year-old female kidney transplant (KT) recipient developed radiologic and biopsy-confirmed cortical necrosis in her transplant with elevated serum creatinine during concurrent chemo-radiotherapy (CRT) for anal squamous cell carcinoma… Click to show full abstract

A 61 year-old female kidney transplant (KT) recipient developed radiologic and biopsy-confirmed cortical necrosis in her transplant with elevated serum creatinine during concurrent chemo-radiotherapy (CRT) for anal squamous cell carcinoma (SCC). Acute anatomical and pathological changes within a transplanted kidney during CRT have not been described in the literature previously. Further research is required to ascertain the potential significance and long-term clinical consequences of such findings.

Keywords: kidney; kidney transplant; cortical necrosis; transplant cortical; radiation

Journal Title: Practical radiation oncology
Year Published: 2021

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