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Refining the resolution of craniofacial dysmorphology in bipolar disorder as an index of brain dysmorphogenesis

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Highlights • Facial dysmorphology was studied as an accessible index of brain dysmorphogenesis.• Bipolar patients showed complex, non-linear changes relative to control subjects.• Bipolar disorder was characterised by retrusion of… Click to show full abstract

Highlights • Facial dysmorphology was studied as an accessible index of brain dysmorphogenesis.• Bipolar patients showed complex, non-linear changes relative to control subjects.• Bipolar disorder was characterised by retrusion of the frontonasal prominences.• The findings indicate dysmorphogenesis in bipolar disorder during early fetal life.

Keywords: dysmorphology; dysmorphogenesis; bipolar disorder; index brain; brain dysmorphogenesis

Journal Title: Psychiatry Research
Year Published: 2020

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