LAUSR

Abstract: Background Valerian root is an herbal supplement used for its anxiolytic and sedative properties. Its extract is thought to serve as an allosteric modulator of gamma-aminobutyric acid A, which can cause delirium due to its influence on the nervous system’s inhibitory tone and its effect on the sleep-wake cycle. Objective This report presents a patient who developed delirium secondary to withdrawal from valerian root. Conclusion This report emphasizes the importance of screening for use and abstinence of herbal supplements when delirium develops, as herbal supplement withdrawal can be an uncommon and overlooked etiology of delirium.