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Actin Nanobodies Uncover the Mystery of Actin Filament Dynamics in Toxoplasma gondii.

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While the intracellular parasite Toxoplasma relies on a divergent actomyosin motor to support unique speeds in directional movement, the dynamics and architecture of parasite actin filaments remain a much-discussed issue.… Click to show full abstract

While the intracellular parasite Toxoplasma relies on a divergent actomyosin motor to support unique speeds in directional movement, the dynamics and architecture of parasite actin filaments remain a much-discussed issue. Using actin chromobodies, Periz et al. started to unveil how networks of dynamic F-actin connect Toxoplasma progeny and expand in the replicative vacuole.

Keywords: uncover mystery; nanobodies uncover; actin nanobodies; filament dynamics; actin filament; mystery actin

Journal Title: Trends in parasitology
Year Published: 2017

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