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Alive and Ticking: Trypanosoma brucei Assaults the Circadian Clocks.

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Rijo-Ferreira et al. report alterations of circadian rhythmicity at the behavioral, tissue, cellular, and molecular levels in mice after Trypanosoma brucei infection, showing that targeting cell clocks is a specific… Click to show full abstract

Rijo-Ferreira et al. report alterations of circadian rhythmicity at the behavioral, tissue, cellular, and molecular levels in mice after Trypanosoma brucei infection, showing that targeting cell clocks is a specific feature of these parasites. Thus, African trypanosomes cause a severe disease by disrupting time-keeping mechanisms and their synchrony.

Keywords: ticking trypanosoma; assaults circadian; brucei assaults; trypanosoma brucei; circadian clocks; alive ticking

Journal Title: Trends in parasitology
Year Published: 2018

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