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PF4 (platelet factor 4) is the first host defense peptide identified from platelets that kills malaria parasites. In a recent study, a cyclic PF4 derivative, cPF4PD, is developed, which inherits… Click to show full abstract
PF4 (platelet factor 4) is the first host defense peptide identified from platelets that kills malaria parasites. In a recent study, a cyclic PF4 derivative, cPF4PD, is developed, which inherits the antiparasitic effect of PF4 but excludes its potential side effects. cPF4PD is a promising novel antimalarial agent of human origin.
Keywords:
defense;
novel defense;
defense peptides;
malaria parasites;
peptides platelets;
platelets kill
Journal Title: Trends in parasitology
Year Published: 2018
Link to full text (if available)
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Journal Title: Trends in parasitology
Year Published: 2018
Link to full text (if available)
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recommendations!