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Gut-microbiota-derived extracellular vesicles: Overlooked mediators in host-helminth interactions?

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Helminth infections impact the composition of the mammalian gut microbiota; however, the mechanisms underpinning these interactions are, thus far, unknown. In this article, we propose that microbiota-derived extracellular vesicles might… Click to show full abstract

Helminth infections impact the composition of the mammalian gut microbiota; however, the mechanisms underpinning these interactions are, thus far, unknown. In this article, we propose that microbiota-derived extracellular vesicles might represent key players in host-helminth-microbiome crosstalk, and outline future directions to elucidate their role(s) in host-parasite relationships.

Keywords: extracellular vesicles; host helminth; microbiota; derived extracellular; gut microbiota; microbiota derived

Journal Title: Trends in parasitology
Year Published: 2021

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