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In vitro cytotoxicity study and anti-Brucella activity of Tarenna asiatica (L)

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Abstract Tarenna asiatica (L), widely used medicinal plants in the treatment of eye infections, skin problems and abdominal pain as a traditional medicine within India and the across the globe.… Click to show full abstract

Abstract Tarenna asiatica (L), widely used medicinal plants in the treatment of eye infections, skin problems and abdominal pain as a traditional medicine within India and the across the globe. Tarenna asiatica has been used to treat a number of disorders, including boils, external ulcers and wounds. The present study aims to evaluate the phytochemical properties and the effects of Tarenna asiatica through In vitro studies. In addition, our study aims to evaluate the anti-cancer activity of the plant extracts against lung cancer cell line (A549) and measure the Anti-Brucella activity of the plant extracts. The plant solvent was extracted for its active chemical components with three different polar solvents using soxhlet apparatus. The quantitative estimation revealed that the ethanol extract of the plant possessed higher phenolics and flavonoids. In vitro studies revealed that the ethanol extract retains higher activity compared to that of the aqueous and petroleum ether extracts. The cancer cell death percentage at 100 mg/ml concentrations of the ethanol and aqueous extracts of T. asiatica ranged between 60% and 67% on lung cancer cell line, respectively.

Keywords: anti brucella; study; tarenna asiatica; brucella activity; activity

Journal Title: South African Journal of Botany
Year Published: 2020

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