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Integration of tri-polar microelectrodes for performance enhancement of an impedance biosensor

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Abstract This paper demonstrates the effect of microelectrodes configuration on the sensitivity and accuracy of the micro-electrical impedance spectroscopy (μEIS). Bi-polar and tri-polar microelectrodes configurations were presented, fabricated and experimentally… Click to show full abstract

Abstract This paper demonstrates the effect of microelectrodes configuration on the sensitivity and accuracy of the micro-electrical impedance spectroscopy (μEIS). Bi-polar and tri-polar microelectrodes configurations were presented, fabricated and experimentally used to extract the electrical parameters of Human Bone Osteosarcoma Epithelial (U2OS) viable and dead cells. A comparison between the experimental results are presented and discussed. These experimental results show that the tri-polar electrode configuration has higher sensitivity compared to bi-polar configuration.

Keywords: microelectrodes performance; performance enhancement; integration tri; tri polar; impedance; polar microelectrodes

Journal Title: Sensing and bio-sensing research
Year Published: 2020

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